James Cook Injury Update
Buffalo Bills running back James Cook, the team's explosive lead rusher, sat out Wednesday's practice session with lingering concerns over a foot injury and a separate ankle issue. This marks the first missed practice for Cook since early in the season, raising eyebrows among Bills Mafia as the team gears up for a crucial divisional clash against the New York Jets on Sunday at Highmark Stadium. Adam Schefter, posting on X (Twitter) via @AdamSchefter, reported that Bills RB James Cook did not practice today due to foot and ankle injuries.
PlayerProfiler NOW+, posting on X(Twitter) via @Profiler_Now, asked: “James Cook missed practice, should you be worried?”
Head coach Sean McDermott confirmed the absence during his post-practice media availability, noting that Cook was held out as a precautionary measure to manage the ailments after he tweaked his foot during last week's narrow 20-17 victory over the New England Patriots.
Cook, who has been a workhorse for Buffalo this year, has racked up 728 rushing yards on 162 carries (4.5 yards per attempt) through nine games, including five touchdowns. He's also chipped in 22 receptions for 187 yards, showcasing his versatility in offensive coordinator Joe Brady's scheme. However, the 25-year-old has dealt with minor nicks and bruises throughout the 2025 campaign, including a brief shoulder scare in Week 6 that didn't sideline him. The foot problem reportedly stems from a hyperextension in the Patriots game, while the ankle stems from ongoing maintenance to prevent a recurrence of last year's mild sprain.
McDermott expressed optimism, stating, "James is day-to-day, and we're taking it slow to ensure he's at his best. We've got depth in the backfield, but we all know what he brings to the table." Backup Ty Johnson and rookie Ray Davis stepped up during drills, with Johnson handling first-team reps and showing crisp cuts in the absence of Cook. The Bills' run game has been pivotal in their 6-3 start, ranking seventh in the NFL with 138.2 yards per game, so Cook's status looms large for maintaining momentum in the AFC East race.
Disclaimer
This content is based on the latest available reports and statements from the Buffalo Bills as of November 6, 2025. Injury details and return timelines are subject to change. For official updates, always refer to team sources or NFL announcements. This information is intended solely for news and informational purposes.




